SCHEMBL14727240

SCHEMBL14727240

Cc1ccc(/C=C/c2ccc(N(c3ccc(-c4ccc(N(c5ccc(/C=C/c6ccc(C)cc6)cc5)c5c(C)cc(C)cc5C)cc4)cc3)c3c(C)cc(C)cc3C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.44
PTGS2 P35354 2/20 0.44
ALOX5 P09917 1/20 0.44
NFE2L2 Q16236 6/20 0.41
RELA Q04206 2/20 0.39
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4402220 0.95 PTGS1 (0.48) PTGS1PTGS2ALOX5NFE2L2RELA
SCHEMBL12128432 0.93 PTGS1 (0.39) PTGS1PTGS2ALOX5NFE2L2RELA
SCHEMBL15496879 0.90 RELA (0.49) PTGS1PTGS2ALOX5NFE2L2RELA
SCHEMBL22139555 0.90 PTGS1 (0.44) PTGS1PTGS2ALOX5NFE2L2RELA
SCHEMBL15854767 0.89 ALDH1A1 (0.41) MAPTMEN1KMT2A
SCHEMBL12018764 0.89 ALDH1A1 (0.41) MAPTMEN1KMT2A
SCHEMBL15854806 0.89 ALDH1A1 (0.41) MAPTMEN1KMT2A
SCHEMBL19607552 0.89 ALDH1A1 (0.41) MAPTMEN1KMT2A
SCHEMBL15854803 0.89 ALDH1A1 (0.41) MAPTMEN1KMT2A
SCHEMBL13308477 0.88 NFE2L2 (0.41) PTGS1PTGS2ALOX5NFE2L2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-10203616-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2019-02-12 US disclosed
US-20170285498-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-05 US disclosed
US-20170285498-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-05 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed