SCHEMBL14727261

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14474560	0.88	SIRT2 (0.48)	MAPTKDM4ECYP1A2CYP3A4CYP2D6
	SCHEMBL14475007	0.88	ABCG2 (0.44)	MAPTNPSR1KDM4ECYP1A2CYP3A4
	SCHEMBL14474537	0.88	SIRT2 (0.47)	MAPTNPSR1KDM4ECYP1A2CYP3A4
	SCHEMBL14727108	0.86	MAPT (0.52)	MAPTNPSR1NPC1RAB9AGBA1
	SCHEMBL14475023	0.84	ABCG2 (0.46)	MAPTNPSR1GBA1KDM4ECYP1A2
	SCHEMBL14475010	0.84	MAPK8 (0.46)	MAPTKDM4EMAPK10MAPK8ABCG2
	SCHEMBL14726046	0.83	ABCG2 (0.51)	MAPTNPSR1KDM4ECYP1A2CYP3A4
	SCHEMBL2156495	0.83	ABCG2 (0.48)	MAPTNPSR1GBA1KDM4ECYP1A2
	SCHEMBL14475087	0.82	PDE5A (0.48)	MAPTNPSR1GBA1KDM4ECYP1A2
	SCHEMBL2154791	0.82	MAPT (0.52)	MAPTNPSR1GBA1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.