SCHEMBL14727467

SCHEMBL14727467

CC(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@H](O)C2OCOCOCCC#N)c(=O)n1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ MTOR P42345 1/20 0.41
▸ MDM2 Q00987 1/20 0.41
▸ NCOA1 Q15788 1/20 0.41
▸ NCOA3 Q9Y6Q9 1/20 0.41
▸ P2RY6 Q15077 7/20 0.37
▸ P2RY14 Q15391 2/20 0.37
▸ NT5E P21589 1/20 0.37
▸ P2RY2 P41231 5/20 0.36
▸ P2RY4 P51582 5/20 0.36
▸ POLB P06746 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ CDA P32320 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15850638 1.00 LMNA (0.41) LMNATHRBMTORMDM2NCOA1
SCHEMBL19981003 1.00 LMNA (0.41) LMNATHRBMTORMDM2NCOA1
SCHEMBL18902462 1.00 LMNA (0.41) LMNATHRBMTORMDM2NCOA1
SCHEMBL21970361 1.00 LMNA (0.41) LMNATHRBMTORMDM2NCOA1
SCHEMBL24024592 1.00 LMNA (0.41) LMNATHRBMTORMDM2NCOA1
SCHEMBL24024770 1.00 LMNA (0.41) LMNATHRBMTORMDM2NCOA1
SCHEMBL24024883 0.98 LMNA (0.43) LMNATHRBMTORMDM2NCOA1
SCHEMBL24024879 0.98 LMNA (0.43) LMNATHRBMTORMDM2NCOA1
SCHEMBL15892158 0.94 P2RY6 (0.37) P2RY6P2RY14NT5EP2RY2P2RY4
SCHEMBL17853310 0.94 P2RY6 (0.37) P2RY6P2RY14NT5EP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079768-A1 METHOD FOR PRODUCING GLYCOSIDE COMPOUNDS BONAC CORPORATION (JP) 2018-03-22 — — US disclosed
US-9481702-B2 Glycoside compound, method for producing thioether, ether, method for producing ether, method for producing glycoside compound, method for producing nucleic acid BONAC CORPORATION (JP) 2016-11-01 — — US disclosed
US-20140206856-A1 GLYCOSIDE COMPOUND, METHOD FOR PRODUCING THIOETHER, ETHER, METHOD FOR PRODUCING ETHER, METHOD FOR PRODUCING GLYCOSIDE COMPOUND, METHOD FOR PRODUCING NUCLEIC ACID BONAC CORPORATION (JP) 2014-07-24 — — US disclosed
WO-2013027843-A1 GLUCOSIDE COMPOUND, METHOD FOR PRODUCING THIOETHER, ETHER, METHOD FOR PRODUCING ETHER, METHOD FOR PRODUCING GLUCOSIDE COMPOUND, METHOD FOR PRODUCING NUCLEIC ACID 株式会社ボナック (JP) 2013-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140206856-A1 GLYCOSIDE COMPOUND, METHOD FOR PRODUCING THIOETHER, ETHER, METHOD FOR PRODUCING ETHER, METHOD FOR PRODUCING GLYCOSIDE COMPOUND, METHOD FOR PRODUCING NUCLEIC ACID DDOST, TENT4A, TRDMT1 LMNA 2625/4885THRB 1261/4885MTOR 2507/4885
US-20180079768-A1 METHOD FOR PRODUCING GLYCOSIDE COMPOUNDS TST, DIMT1, DERA LMNA 3184/4885THRB 3329/4885MTOR 1087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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