Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561657 | 0.99 | THRB (0.70) | THRBADORA3KMT2APLA2G1BATG4B | |
| SCHEMBL14173037 | 0.86 | THRB (0.46) | THRBADORA3KMT2AMEN1TSHR | |
| SCHEMBL14173038 | 0.85 | ESR1 (0.47) | THRBADORA3KMT2AMEN1TSHR | |
| SCHEMBL4596017 | 0.85 | THRB (1.00) | THRBKMT2APLA2G1BATG4BMEN1 | |
| SCHEMBL7218282 | 0.84 | THRB (0.48) | THRBADORA3KMT2APLA2G1BATG4B | |
| SCHEMBL7787037 | 0.83 | THRB (0.97) | THRBKMT2APLA2G1BATG4BMEN1 | |
| SCHEMBL7219066 | 0.82 | THRB (0.47) | THRBADORA3KMT2APLA2G1BATG4B | |
| SCHEMBL7212815 | 0.81 | THRB (0.90) | THRBKMT2APLA2G1BATG4BMEN1 | |
| SCHEMBL815739 | 0.81 | THRB (0.90) | THRBKMT2APLA2G1BATG4BMEN1 | |
| SCHEMBL11987131 | 0.80 | ADORA3 (0.44) | THRBADORA3KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141094-B1 | CYCLOSILOXANE-BASED CROSS-LINKABLE MONOMERS, PRODUCTION THEREOF AND USE THEREOF IN POLYMERISABLE MATERIALS | 3M ESPE AG (DE) | 2002-07-24 | — | — | EP | disclosed |