SCHEMBL14727976

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14727832	0.92	CYP1A2 (0.61)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL17214443	0.85	ABCG2 (0.56)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL14727835	0.84	ALDH1A1 (0.53)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL14475167	0.83	MEN1 (0.64)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL16183452	0.83	CYP1A2 (0.64)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL14727837	0.83	ABCG2 (0.56)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL14475208	0.83	CYP1A2 (0.64)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL14475229	0.83	CYP1A2 (0.64)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL14474995	0.83	ALDH1A1 (0.61)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4
	SCHEMBL14475854	0.83	CYP1A2 (0.65)	CYP1A2CYP3A4ALDH1A1CYP2C9CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.