SCHEMBL14727979

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14474120	0.94	CYP3A4 (0.46)	FKBP1AUSP2CYP3A4CYP1A2CYP2D6
	SCHEMBL14727996	0.92	ALDH1A1 (0.51)	ALDH1A1HPGDCYP3A4CYP1A2CYP2D6
	SCHEMBL14475887	0.86	CYP3A4 (0.46)	ALDH1A1USP2HPGDCYP3A4CYP1A2
	SCHEMBL14727503	0.86	MAPT (0.55)	ALDH1A1HPGDCYP3A4CYP1A2CYP2D6
	SCHEMBL14474096	0.85	GAA (0.46)	ALDH1A1HPGDCYP3A4CYP1A2CYP2D6
	SCHEMBL2154778	0.84	CYP1A2 (0.57)	ALDH1A1USP2CYP3A4CYP1A2CYP2D6
	SCHEMBL14727501	0.83	MAPT (0.51)	ALDH1A1HPGDCYP3A4CYP1A2CYP2D6
	SCHEMBL14727997	0.83	GBA1 (0.45)	ALDH1A1USP2CYP3A4CYP1A2CYP2D6
	SCHEMBL14475863	0.81	PDE5A (0.51)	HPGDCYP3A4CYP1A2CYP2D6LMNA
	SCHEMBL14474060	0.81	EGFR (0.48)	FKBP1AHPGDCYP3A4CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.