SCHEMBL14728002

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8199094	0.84	PARP1 (0.55)	CYP11B1CYP11B2PARP1GRIN2DGRIN3B
	SCHEMBL8190059	0.80	PARP1 (0.38)	CYP11B1CYP11B2PARP1PDE3BPDE3A
	SCHEMBL293956	0.78	CYP11B1 (0.41)	CYP11B1CYP11B2CA12CA2CA4
	SCHEMBL30646022	0.78	CYP11B1 (0.41)	CYP11B1CYP11B2CA12CA2CA4
	SCHEMBL2811609	0.75	AHR (0.56)	CA9PDE3BPDE3A
	SCHEMBL3586629	0.75	CA9 (0.54)	CYP11B1CYP11B2PRF1CA12CA2
	SCHEMBL436631	0.75	MMP12 (0.51)	CYP11B1CYP11B2ACHEPARP1PDE3B
	SCHEMBL15788033	0.75	CYP11B1 (0.41)	CYP11B1CYP11B2GRIN2DGRIN3BGRIN1
	SCHEMBL3586627	0.75	CYP11B1 (0.41)	CYP11B1CYP11B2GRIN2DGRIN3BGRIN1
	SCHEMBL29746650	0.75	AHR (0.56)	CA9PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.