SCHEMBL14728162

SCHEMBL14728162

c1ccc(-c2ccc(-c3ccc4c(c3)c3ccccc3c3cc5c(cc43)c3ccccc3n5-c3ccccc3)nc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
KMT2A Q03164 2/20 0.33
MTOR P42345 1/20 0.33
IL1R1 P14778 1/20 0.33
HDAC4 P56524 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
PTGER4 P35408 1/20 0.32
HPGDS O60760 1/20 0.32
AXL P30530 1/20 0.32
CDK8 P49336 1/20 0.32
TNIK Q9UKE5 1/20 0.32
GSK3B P49841 1/20 0.32
AVPR1A P37288 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12496047 0.91 L3MBTL1 (0.47) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL25017025 0.89 L3MBTL1 (0.45) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL786942 0.88 L3MBTL1 (0.53) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL18560754 0.88 KDM4E (0.44) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL16405420 0.88 KDM4E (0.44) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL16726756 0.88 KDM4E (0.44) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL14728159 0.87 KDM4E (0.41) L3MBTL1KDM4EATMALDH1A1HTT
SCHEMBL18560799 0.86 L3MBTL1 (0.45) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL16726732 0.86 L3MBTL1 (0.47) L3MBTL1KDM4EATMHSD17B1HSD17B2
SCHEMBL18790304 0.86 L3MBTL1 (0.47) L3MBTL1KDM4EATMHSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 L3MBTL1 2318/4885KDM4E 1626/4885ATM 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.