SCHEMBL14728159

SCHEMBL14728159

c1ccc(-n2c3ccccc3c3cc4c5ccc(-c6ccc(-c7ccccn7)nc6)cc5c5ccccc5c4cc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
HPGDS O60760 2/20 0.38
NPY5R Q15761 1/20 0.36
METAP2 P50579 1/20 0.34
GRM5 P41594 2/20 0.33
MCL1 Q07820 2/20 0.32
LMNA P02545 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
POLB P06746 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728162 0.87 L3MBTL1 (0.44) KDM4EL3MBTL1ATMHPGDSALDH1A1
SCHEMBL12496047 0.86 L3MBTL1 (0.47) KDM4EL3MBTL1ATMNPC1RAB9A
SCHEMBL24940364 0.85 HPGDS (0.33) KDM4EL3MBTL1ATMHPGDSNPY5R
SCHEMBL24626321 0.84 L3MBTL1 (0.39) KDM4EL3MBTL1ATMHPGDSNPY5R
SCHEMBL24626174 0.84 L3MBTL1 (0.39) KDM4EL3MBTL1ATMHPGDSNPY5R
SCHEMBL24344945 0.84 KDM4E (0.39) KDM4EL3MBTL1ATMHPGDSNPY5R
SCHEMBL24626123 0.84 L3MBTL1 (0.39) KDM4EL3MBTL1ATMHPGDSNPY5R
SCHEMBL16405420 0.82 KDM4E (0.44) KDM4EL3MBTL1ATMNPC1RAB9A
SCHEMBL15034570 0.81 HTR1A (0.43) KDM4EL3MBTL1ATMNPY5RMETAP2
SCHEMBL16726757 0.81 KDM4E (0.43) KDM4EL3MBTL1ATMNPY5RMETAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 KDM4E 1626/4885L3MBTL1 2318/4885ATM 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.