SCHEMBL14728171

SCHEMBL14728171

c1ccc(-n2c3ccccc3c3cc4c5ccc(N(c6ccc7ccccc7c6)c6ccc7ccccc7c6)cc5c5ccccc5c4cc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
PRSS1 P07477 1/20 0.35
PER2 O15055 1/20 0.34
CRY1 Q16526 1/20 0.34
CRY2 Q49AN0 1/20 0.34
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
PDE7A Q13946 1/20 0.31
MAPK1 P28482 1/20 0.31
BACE1 P56817 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728167 0.94 L3MBTL1 (0.41) KDM4EATML3MBTL1F2F10
SCHEMBL31639 0.91 KDM4E (0.50) KDM4EATML3MBTL1F2F10
SCHEMBL14728185 0.91 KDM4E (0.40) KDM4EATML3MBTL1F2F10
SCHEMBL8928247 0.91 KDM4E (0.53) KDM4EATML3MBTL1F2F10
SCHEMBL10087124 0.91 KDM4E (0.53) KDM4EATML3MBTL1F2F10
SCHEMBL14728175 0.90 KDM4E (0.37) KDM4EATML3MBTL1F2F10
SCHEMBL31635 0.90 KDM4E (0.49) KDM4EATML3MBTL1F2F10
SCHEMBL24539865 0.89 KDM4E (0.51) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL14728182 0.89 KDM4E (0.51) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL16202908 0.89 KDM4E (0.51) KDM4EATML3MBTL1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 KDM4E 1626/4885ATM 4087/4885L3MBTL1 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.