Sugi Predict

Sugi Predict / Compounds / SCHEMBL14728182

SCHEMBL14728182

SCHEMBL14728182

c1ccc(N(c2ccccc2)c2ccc3c(c2)c2ccccc2c2cc4c(cc32)c2ccccc2n4-c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.51
▸ L3MBTL1 Q9Y468 3/20 0.51
▸ ATM Q13315 1/20 0.51
▸ MAPK8 P45983 2/20 0.35
▸ MAPK1 P28482 1/20 0.34
▸ HSD17B10 Q99714 2/20 0.33
▸ ALDH1A1 P00352 4/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ GLA P06280 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ PGR P06401 3/20 0.32
▸ IL1R1 P14778 1/20 0.32
▸ KDR P35968 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16202908 1.00 KDM4E (0.51) KDM4EL3MBTL1ATMMAPK8MAPK1
SCHEMBL24539865 1.00 KDM4E (0.51) KDM4EL3MBTL1ATMMAPK8MAPK1
SCHEMBL17725477 0.94 KDM4E (0.55) KDM4EL3MBTL1ATMMAPK8MAPK1
SCHEMBL18688729 0.94 KDM4E (0.55) KDM4EL3MBTL1ATMMAPK8MAPK1
SCHEMBL18689444 0.94 KDM4E (0.55) KDM4EL3MBTL1ATMMAPK8MAPK1
SCHEMBL14728154 0.93 L3MBTL1 (0.47) KDM4EL3MBTL1ATMMAPK8MAPK1
SCHEMBL12117314 0.93 KDM4E (0.56) KDM4EL3MBTL1ATMMAPK8MAPK1
SCHEMBL14728174 0.92 L3MBTL1 (0.42) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL18716752 0.91 L3MBTL1 (0.43) KDM4EL3MBTL1ATMMAPK8ALDH1A1
SCHEMBL20904347 0.91 KDM4E (0.55) KDM4EL3MBTL1ATMMAPK8HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9917262-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-13 — — US disclosed
US-9917262-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-13 — — US disclosed
US-20160133853-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LT.D (KR) 2016-05-12 — — US disclosed
US-20160133853-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LT.D (KR) 2016-05-12 — — US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 — — US disclosed
US-9017829-B2 Phenanthrocarbazole compound, and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2015-04-28 — — US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 — — US disclosed
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2013-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048975-A1 PHENANTHROCARBAZOLE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME PPOX, ORC3, CACNA2D3 KDM4E 1626/4885L3MBTL1 2318/4885ATM 4087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.