SCHEMBL147287

SCHEMBL147287

CCCCCC(O)N(c1ccc(C)cc1)C(O)CCCCC

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE5A O76074 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 1/20 0.36
CNR2 P34972 1/20 0.36
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
MCHR1 Q99705 1/20 0.35
CSNK1E P49674 1/20 0.35
RAB9A P51151 2/20 0.34
GPR84 Q9NQS5 3/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
GPX4 P36969 1/20 0.33
PAX8 Q06710 1/20 0.33
GCGR P47871 1/20 0.33
KCNH2 Q12809 1/20 0.33
HPGD P15428 1/20 0.33
SPHK1 Q9NYA1 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603382 0.86 ALDH1A1 (0.44) ALDH1A1TSHRRAB9A
SCHEMBL146242 0.80 ALDH1A1 (0.41) ALDH1A1TSHRRAB9A
SCHEMBL28932709 0.79 NAAA (0.41) CSNK1EGPR84NPC1SPHK1
SCHEMBL15202115 0.78 CYP3A4 (0.44) L3MBTL1ALDH1A1TSHRCSNK1ERAB9A
Hexane SCHEMBL10767821 0.75 ALDH1A1 (0.48) L3MBTL1HTTCNR2ALDH1A1TSHR
SCHEMBL6207044 0.75 S1PR2 (0.46) PDE5AL3MBTL1HTTALDH1A1KCNH2
Hydroquinone SCHEMBL8038441 0.74 ACHE (0.48) L3MBTL1ALDH1A1TSHRRAB9ANPC1
SCHEMBL12420337 0.73 S1PR2 (0.48) PDE5AL3MBTL1HTTKCNH2
SCHEMBL14717561 0.73 S1PR2 (0.48) PDE5AL3MBTL1HTTKCNH2
SCHEMBL2084176 0.73 S1PR2 (0.48) PDE5AL3MBTL1HTTKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390273-B1 DUAL-CURE CURABLE MATERIAL KIT TOKUYAMA DENTAL CORP (JP) 2015-11-04 EP disclosed
US-8993652-B2 Dual-cure curable material kit TOKUYAMA DENTAL CORPORATION (JP) 2015-03-31 US disclosed
US-20120059079-A1 DUAL-CURE CURABLE MATERIAL KIT TOKUYAMA DENTAL CORPORATION (JP) 2012-03-08 US disclosed
EP-2390273-A1 DUAL-CURE CURABLE MATERIAL KIT Tokuyama Dental Corporation (JP) 2011-11-30 EP disclosed
US-20110255272-A1 Simulated candle apparatus PRIVAS YVES 2011-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059079-A1 DUAL-CURE CURABLE MATERIAL KIT KIT, DSTYK, H1-5 PDE5A 2078/4885L3MBTL1 3425/4885HTT 1579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.