Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728816 | 0.81 | KDM4E (0.44) | KDM4EMAPTALDH1A1HTTBLM | |
| SCHEMBL14728838 | 0.77 | MAPT (0.54) | KDM4EMAPTALDH1A1HTTBLM | |
| SCHEMBL11404116 | 0.75 | ALDH1A1 (0.57) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11404117 | 0.75 | ALDH1A1 (0.57) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL14728836 | 0.74 | KMT2A (0.44) | KDM4EMAPTALDH1A1HTTBLM | |
| SCHEMBL14728840 | 0.74 | MAOB (0.43) | KDM4EMAPTALDH1A1HTTBLM | |
| SCHEMBL14728832 | 0.73 | CHRM5 (0.49) | KDM4EMAPTALDH1A1HTTBLM | |
| SCHEMBL13479628 | 0.70 | MEN1 (0.60) | KDM4EMAPTALDH1A1HTTBLM | |
| SCHEMBL14728791 | 0.68 | PKM (0.54) | KDM4EMAPTALDH1A1HTTBLM | |
| SCHEMBL4752345 | 0.68 | GRIN2D (0.40) | KDM4EMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026357-A1 | PREPARATION METHOD OF IMIDAZOLE DERIVATIVES | 北京欧博方医药科技有限公司 (CN) | 2013-02-28 | — | — | WO | disclosed |