Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728791 | 0.83 | PKM (0.54) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL14728836 | 0.83 | KMT2A (0.44) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL14728802 | 0.81 | RAB9A (0.49) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL14728832 | 0.81 | CHRM5 (0.49) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL14728822 | 0.79 | APP (0.46) | MAPTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL14728847 | 0.77 | KDM4E (0.44) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL14728816 | 0.77 | KDM4E (0.44) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL15209207 | 0.76 | KMT2A (0.42) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL15209208 | 0.76 | KMT2A (0.42) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL14728827 | 0.76 | KMT2A (0.41) | MAPTRAB9AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026357-A1 | PREPARATION METHOD OF IMIDAZOLE DERIVATIVES | 北京欧博方医药科技有限公司 (CN) | 2013-02-28 | — | — | WO | disclosed |