Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP3 | P08254 | 4/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729018 | 0.94 | GPR119 (0.39) | GPR119ENPP2MMP2MMP3JAK1 | |
| SCHEMBL14729173 | 0.93 | GPR119 (0.37) | GPR119ENPP2MMP2MMP3JAK1 | |
| SCHEMBL14729140 | 0.92 | GPR119 (0.46) | GPR119MMP2MMP3 | |
| SCHEMBL14729170 | 0.91 | GPR119 (0.38) | GPR119MMP2MMP3JAK1LIPC | |
| SCHEMBL14729015 | 0.88 | GPR119 (0.37) | GPR119MMP2MMP3JAK1LIPC | |
| SCHEMBL14729012 | 0.87 | GPR119 (0.38) | GPR119MMP2MMP3LIPCLIPG | |
| SCHEMBL14728999 | 0.87 | GPR119 (0.52) | GPR119ENPP2 | |
| SCHEMBL14728889 | 0.86 | GPR119 (0.47) | GPR119MMP2MMP3 | |
| SCHEMBL14729001 | 0.85 | GPR119 (0.51) | GPR119 | |
| SCHEMBL14728903 | 0.84 | GPR119 (0.49) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940716-B2 | Bicyclic heteroaryl compounds as GPR119 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-01-27 | — | — | US | disclosed |
| US-20130053345-A1 | BICYCLIC HETEROARLY ANALOGUES AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053345-A1 | BICYCLIC HETEROARLY ANALOGUES AS GPR119 MODULATORS | GPR119, GPR139, GPR4 | GPR119 1/4885ENPP2 270/4885MMP2 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.