SCHEMBL14729341

SCHEMBL14729341

COC(=O)CN(CC(=O)OC)CC(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA14 Q9ULX7 3/20 0.41
CA2 P00918 2/20 0.41
DGAT1 O75907 1/20 0.40
TSHR P16473 3/20 0.39
NR1D1 P20393 5/20 0.36
HSD17B10 Q99714 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
CYP2D6 P10635 1/20 0.35
TET2 Q6N021 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NR1H3 Q13133 1/20 0.34
CA1 P00915 2/20 0.33
CA7 P43166 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13965219 1.00 CA12 (0.41) CA12CA14CA2DGAT1TSHR
SCHEMBL27420033 0.91 NR1D1 (0.38) CA12CA14CA2DGAT1NR1D1
SCHEMBL29484958 0.90 CA14 (0.38) CA12CA14CA2DGAT1TSHR
SCHEMBL15548847 0.86 NR1D1 (0.36) CA12CA14CA2DGAT1NR1D1
SCHEMBL18362360 0.84 KMT2A (0.47) CA12CA14CA2DGAT1TSHR
SCHEMBL63502 0.83 TSHR (0.53) CA12CA14CA2TSHRHSD17B10
SCHEMBL419703 0.83 TDP1 (0.42) CA2DGAT1TSHRNR1D1HSD17B10
SCHEMBL18145576 0.83 TDP1 (0.42) CA2DGAT1TSHRNR1D1HSD17B10
SCHEMBL22737498 0.82 CYP2D6 (0.35) CA12CA14CA2DGAT1NR1D1
SCHEMBL1688828 0.82 CA14 (0.41) CA12CA14CA2DGAT1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 CA12 20/4885CA14 13/4885CA2 153/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 CA12 19/4885CA14 13/4885CA2 270/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA12 40/4885CA14 25/4885CA2 1257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.