SCHEMBL419703

SCHEMBL419703

CC(C)(C)OC(=O)CN(CC(=O)O)CC(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.42
EYA2 O00167 1/20 0.42
APP P05067 1/20 0.42
ACE P12821 1/20 0.42
BLM P54132 2/20 0.41
PMP22 Q01453 2/20 0.41
ALOX15 P16050 2/20 0.41
TSHR P16473 2/20 0.41
CYP2C19 P33261 2/20 0.41
ADRA1A P35348 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.41
ADRA2A P08913 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145576 1.00 TDP1 (0.42) TDP1EYA2APPACEBLM
SCHEMBL27420033 0.91 NR1D1 (0.38) TDP1CA1CA2NR1D1NR1H3
SCHEMBL992084 0.90 TDP1 (0.58) TDP1EYA2APPACEBLM
SCHEMBL2137303 0.90 TDP1 (0.38) TDP1EYA2APPACEBLM
SCHEMBL4621864 0.90 TDP1 (0.58) TDP1EYA2APPACEBLM
SCHEMBL438113 0.90 TDP1 (0.58) TDP1EYA2APPACEBLM
SCHEMBL19952793 0.87 TDP1 (0.45) TDP1EYA2APPACEBLM
SCHEMBL6227790 0.87 TDP1 (0.45) TDP1EYA2APPACEBLM
SCHEMBL15548847 0.86 NR1D1 (0.36) TDP1CA1CA2NR1D1NR1H3
SCHEMBL2185399 0.85 TDP1 (0.43) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972649-B1 MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE NOVARTIS AG (CH) 2026-05-13 EP disclosed
US-12527886-B2 Radiopharmaceuticals and composition for thrombus imaging THE ASAN FOUNDATION (KR) 2026-01-20 US disclosed
EP-4566608-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2025-06-11 EP disclosed
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2025-06-05 US disclosed
EP-4445900-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
EP-4440702-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
WO-2025095479-A1 NOVEL PROSTATE SPECIFIC MEMBRANE ANTIGEN LIGAND AND USE THEREOF 서울대학교병원 2025-05-08 WO disclosed
US-12187753-B2 Therapeutics compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-01-07 US disclosed
EP-4445900-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2024-10-16 EP disclosed
EP-4440702-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 EP disclosed
US-20120021973-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2012-01-26 US disclosed
US-20120021973-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2012-01-26 US disclosed
EP-2370104-A1 PEPTIDES FOR TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2011-10-05 EP disclosed
WO-2011104378-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2011-09-01 WO disclosed
WO-2011104378-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2011-09-01 WO disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
WO-2010060901-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2010-06-03 WO disclosed
WO-2010060901-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2010-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021973-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R TDP1 4770/4885EYA2 2451/4885APP 1563/4885
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS TDP1 1611/4885EYA2 3195/4885APP 980/4885
US-12187753-B2 Therapeutics compounds for HIV virus infection CD4, HAVCR2, MAVS TDP1 1611/4885EYA2 3195/4885APP 980/4885
US-20100173835-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R TDP1 4770/4885EYA2 2451/4885APP 1563/4885
US-12527886-B2 Radiopharmaceuticals and composition for thrombus imaging F11, CD274, SERPINC1 TDP1 3450/4885EYA2 4648/4885APP 2712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.