Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13811606 | 0.83 | LMNA (0.39) | OPRM1LMNADNM1CA2FDPS | |
| SCHEMBL278027 | 0.79 | OPRM1 (0.42) | OPRM1LMNACA1DNM1CA2 | |
| SCHEMBL28028850 | 0.78 | OPRM1 (0.33) | OPRM1LMNACA1DNM1CA2 | |
| SCHEMBL27973135 | 0.77 | — | — | |
| SCHEMBL1678691 | 0.75 | LMNA (0.41) | OPRM1LMNACA1CA2FDPS | |
| SCHEMBL13267762 | 0.75 | CA1 (0.40) | OPRM1LMNACA1CA2FDPS | |
| SCHEMBL7877396 | 0.73 | CA2 (0.42) | LMNACA1DNM1CA2FDPS | |
| SCHEMBL8516921 | 0.73 | CA2 (0.42) | LMNACA1DNM1CA2FDPS | |
| SCHEMBL8008721 | 0.73 | CA2 (0.42) | LMNACA1DNM1CA2FDPS | |
| SCHEMBL6578817 | 0.73 | CA2 (0.42) | LMNACA1DNM1CA2FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027845-A1 | RADIOLABELED COMPOUNDS AND THEIR USE AS RADIOTRACERS FOR QUANTITATIVE IMAGING OF PHOSPHODIESTERASE (PDE10A) IN MAMMALS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |