Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414464 | 0.80 | FKBP1A (0.39) | FKBP1AKDM4E | |
| SCHEMBL6048244 | 0.77 | FKBP1A (0.36) | FKBP1AMCL1 | |
| SCHEMBL2361458 | 0.75 | FKBP1A (0.37) | FKBP1AMCL1 | |
| SCHEMBL535757 | 0.74 | FKBP1A (0.36) | FKBP1AKDM4EMAPK1 | |
| SCHEMBL28226590 | 0.73 | MAPK1 (0.33) | MAPK1 | |
| Methacrylic Acid SCHEMBL424254 | 0.72 | FKBP1A (0.35) | FKBP1AKDM4E | |
| SCHEMBL2058320 | 0.72 | FKBP1A (0.36) | FKBP1AMCL1 | |
| SCHEMBL2057797 | 0.72 | FKBP1A (0.36) | FKBP1AMCL1 | |
| SCHEMBL2057754 | 0.72 | FKBP1A (0.36) | FKBP1AMCL1 | |
| SCHEMBL2057762 | 0.71 | FKBP1A (0.36) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050202067-A1 | Matrix structure and hybrid matrix system for inducing a neofacia, their use and method for generating a neofacia | GKSS FORSCHUNGSZENTRUM (DE) | 2005-09-15 | — | — | US | claimed |
| US-9044531-B2 | Vascular closure device | CORDIS CORPORATION (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140336700-A1 | VASCULAR CLOSURE DEVICE | CORDIS CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
| US-8647393-B2 | Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same | HEALIONICS CORPORATION (US) | 2014-02-11 | — | — | US | disclosed |
| US-20130236502-A1 | IMPLANTABLE MEDICAL DEVICES HAVING MICROPOROUS SURFACE LAYERS AND METHOD FOR REDUCING FOREIGN BODY RESPONSE TO THE SAME | HEALIONICS CORPORATION (US) | 2013-09-12 | — | — | US | disclosed |
| US-8372423-B2 | Implantable medical devices having microporous surface layers and method for reducing foreign body response to the same | HEALIONICS CORPORATION (US) | 2013-02-12 | — | — | US | disclosed |
| US-20110257623-A1 | IMPLANTABLE MEDICAL DEVICES HAVING MICROPOROUS SURFACE LAYERS AND METHOD FOR REDUCING FOREIGN BODY RESPONSE TO THE SAME | HEALIONICS CORPORATION (US) | 2011-10-20 | — | — | US | disclosed |
| US-7914573-B2 | Polymeric stent having modified molecular structures | CORDIS CORPORATION (US) | 2011-03-29 | — | — | US | disclosed |
| US-20080169582-A1 | Method and apparatus for making polymeric drug delivery devices having differing morphological structures | CORDIS CORPORATION | 2008-07-17 | — | — | US | disclosed |
| US-20080102035-A1 | Medical device having discrete regions | CORDIS US CORP | 2008-05-01 | — | — | US | disclosed |
| US-20070203569-A1 | Implantable device formed from polymer blends having modified molecular structures | CORDIS CORPORATION | 2007-08-30 | — | — | US | disclosed |
| US-20070135902-A1 | Polymeric stent having modified molecular structures in the flexible connections | CORDIS CORPORATION | 2007-06-14 | — | — | US | disclosed |