Methacrylic Acid

Methacrylic Acid

SCHEMBL424254

C=C(C)C(=O)O.O=C1OCCCCC1O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 3/20 0.35
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MMP3 P08254 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5522044 0.85
Acrylic Acid SCHEMBL8362777 0.83 LMNA (0.34) FKBP1A
SCHEMBL9807603 0.79
SCHEMBL5818763 0.79
SCHEMBL8943397 0.79
Methacrylic Acid SCHEMBL29615180 0.79 FKBP1A (0.33) FKBP1A
SCHEMBL28049913 0.78 CA1 (0.32) FKBP1A
SCHEMBL12060316 0.78 TSHR (0.40) FKBP1A
Methacrylic Acid SCHEMBL5361816 0.76 FKBP1A (0.34) FKBP1A
Methacrylic Acid SCHEMBL4882592 0.76 CA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735464-B2 Radically curable urethane dimethacrylates and compositions thereof for tougher dental prosthetics PULPDENT CORPORATION (US) 2014-05-27 US claimed
US-20130041067-A1 Radically Curable Urethane Dimethacrylates and Compositions Thereof for Tougher Dental Prosthetics PULPDENT CORPORATION (US) 2013-02-14 US claimed
US-20120021383-A1 Radically Curable Urethane Dimethacrylates and Compositions Thereof for Tougher Dental Prosthetics PULPDENT CORPORATION (US) 2012-01-26 US claimed
US-10179445-B2 Method for producing optical member and use of ultraviolet ray cured resin composition for same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-01-15 US disclosed
US-20150224756-A1 Method For Producing Optical Member And Use Of Ultraviolet Ray Cured Resin Composition For Same NIPPON KAYAKU KK (JP) 2015-08-13 US disclosed
US-20140248498-A1 Method For Producing Optical Member And Use Of Ultraviolet Ray Cured Resin Composition For Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-09-04 US disclosed
US-8735464-B2 Radically curable urethane dimethacrylates and compositions thereof for tougher dental prosthetics PULPDENT CORPORATION (US) 2014-05-27 US disclosed
CN-103534758-A Ultraviolet curable resin composition NIPPON KAYAKU KK 2014-01-22 CN disclosed
US-20130041067-A1 Radically Curable Urethane Dimethacrylates and Compositions Thereof for Tougher Dental Prosthetics PULPDENT CORPORATION (US) 2013-02-14 US disclosed
CN-101203915-B Resin composition for optical disc and cured product thereof NIPPON KAYAKU KK 2012-11-14 CN disclosed
US-8292625-B2 Radically curable urethane dimethacrylates and compositions thereof for tougher dental prosthetics PULPDENT CORPORATION (US) 2012-10-23 US disclosed
US-20120021383-A1 Radically Curable Urethane Dimethacrylates and Compositions Thereof for Tougher Dental Prosthetics PULPDENT CORPORATION (US) 2012-01-26 US disclosed
CN-101203915-A Resin composition for optical disc and cured product thereof NIPPON KAYAKU KK (JP) 2008-06-18 CN disclosed
US-20060223904-A1 Adhesive composition and optical disc prepared therewith NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2006-10-05 US disclosed
US-5536775-A ACRYLATED EPOXY RESIN; PROTECTIVE COATINGS ON FLOORING SANDOZ LTD. (CH) 1996-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021383-A1 Radically Curable Urethane Dimethacrylates and Compositions Thereof for Tougher Dental Prosthetics XRCC6, PUF60, ESD FKBP1A 3109/4885KDM4E 134/4885GAA 3385/4885
US-20130041067-A1 Radically Curable Urethane Dimethacrylates and Compositions Thereof for Tougher Dental Prosthetics XRCC6, PUF60, ESD FKBP1A 3109/4885KDM4E 134/4885GAA 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.