Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.37 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPP5C | P53041 | 1/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181991 | 0.83 | PPM1B (0.49) | PPM1BMAPK1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL17532429 | 0.82 | PPM1B (0.48) | PPM1BMAPK1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3495026 | 0.79 | L3MBTL1 (0.42) | PPM1BL3MBTL1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL13311367 | 0.79 | L3MBTL1 (0.42) | PPM1BL3MBTL1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL13311393 | 0.79 | PPM1B (0.43) | PPM1BMAPK1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12182012 | 0.79 | PPM1B (0.43) | PPM1BMAPK1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13311412 | 0.79 | PPM1B (0.55) | PPM1BMAPK1RAB9AALDH1A1GAA | |
| SCHEMBL17532421 | 0.78 | ALDH1A1 (0.46) | PPM1BL3MBTL1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL13311489 | 0.78 | ALDH1A1 (0.46) | PPM1BL3MBTL1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL17532425 | 0.77 | RAB9A (0.52) | PPM1BL3MBTL1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130047844-A1 | POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-02-28 | — | — | US | disclosed |