Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730240 | 0.88 | GPR119 (0.42) | HRH4GPR119ALOX5APHRH3 | |
| SCHEMBL6125573 | 0.88 | GPR119 (0.38) | HRH4GPR119ALOX5APHRH3 | |
| SCHEMBL12490078 | 0.88 | GPR119 (0.39) | GPR119ALOX5AP | |
| Hydrochloric Acid SCHEMBL14723462 | 0.87 | GPR119 (0.41) | HRH4GPR119ALOX5APHRH3 | |
| Hydrochloric Acid SCHEMBL6125721 | 0.87 | GPR119 (0.37) | HRH4GPR119ALOX5APHRH3 | |
| SCHEMBL14730241 | 0.87 | GPR119 (0.38) | HRH4GPR119ALOX5APHRH3KCNH2 | |
| SCHEMBL14730328 | 0.84 | GPR119 (0.37) | HRH4GPR119ALOX5APKCNH2 | |
| SCHEMBL356316 | 0.81 | GPR119 (0.59) | GPR119ALOX5AP | |
| SCHEMBL14990451 | 0.81 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL14730239 | 0.77 | GPR119 (0.43) | HRH4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |