Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730240 | 0.90 | GPR119 (0.42) | GPR119HRH4ALOX5APHRH3 | |
| SCHEMBL6125573 | 0.90 | GPR119 (0.38) | GPR119HRH4ALOX5APHRH3 | |
| Hydrochloric Acid SCHEMBL6125721 | 0.89 | GPR119 (0.37) | GPR119HRH4ALOX5APHRH3 | |
| Hydrochloric Acid SCHEMBL14723462 | 0.89 | GPR119 (0.41) | GPR119HRH4ALOX5APHRH3 | |
| SCHEMBL14730237 | 0.87 | HRH4 (0.39) | GPR119HRH4KCNH2ALOX5APHRH3 | |
| SCHEMBL8614390 | 0.78 | GPR119 (0.38) | GPR119ALOX5AP | |
| SCHEMBL19434409 | 0.77 | GPR119 (0.46) | GPR119KCNH2ALOX5AP | |
| SCHEMBL470682 | 0.77 | GPR119 (0.46) | GPR119KCNH2ALOX5AP | |
| SCHEMBL14730232 | 0.77 | GPR119 (0.51) | GPR119HRH4 | |
| SCHEMBL19457227 | 0.76 | GPR119 (0.42) | GPR119KCNH2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |