Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.40 |
| ▸ | LCAT | P04180 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730310 | 0.84 | OPRK1 (0.44) | GPR119OPRK1LCATCHRM3PDE4A | |
| SCHEMBL19454413 | 0.82 | GPR119 (0.46) | GPR119OPRK1LCATCHRM3PDE4A | |
| SCHEMBL3694402 | 0.80 | GPR119 (0.59) | GPR119OPRK1LCATCHRM3PDE4A | |
| SCHEMBL19399166 | 0.78 | CHRM3 (0.47) | GPR119LCATCHRM3PDE4APDE4B | |
| SCHEMBL11956862 | 0.78 | CHRM3 (0.45) | GPR119OPRK1LCATCHRM3PDE4A | |
| SCHEMBL6128099 | 0.78 | OPRK1 (0.49) | GPR119OPRK1PDE4APDE4BPDE4C | |
| SCHEMBL14730237 | 0.77 | HRH4 (0.39) | GPR119HRH4 | |
| SCHEMBL14730194 | 0.77 | OPRK1 (0.40) | GPR119OPRK1HRH4 | |
| SCHEMBL6118213 | 0.77 | GPR119 (0.68) | GPR119HRH4 | |
| Hydrochloric Acid SCHEMBL14723195 | 0.76 | OPRK1 (0.39) | GPR119OPRK1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |