Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 8/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730293 | 0.95 | DPP4 (0.32) | MCHR1DPP4WDR5DPP8DPP9 | |
| SCHEMBL14730365 | 0.93 | MCHR1 (0.34) | MCHR1DPP4DPP8DPP9DPP7 | |
| SCHEMBL14730184 | 0.90 | GPR119 (0.36) | MCHR1DPP4CCR5DPP8DPP9 | |
| SCHEMBL14730207 | 0.86 | NTRK1 (0.34) | WDR5MEN1KMT2AVNN1NTRK1 | |
| SCHEMBL14730299 | 0.86 | DPP4 (0.37) | MCHR1DPP4CCR5DPP8DPP9 | |
| SCHEMBL14730287 | 0.85 | ALOX5AP (0.37) | MCHR1DPP4CCR5DPP8DPP9 | |
| SCHEMBL14730186 | 0.85 | GPR119 (0.36) | MCHR1DPP4WDR5DPP8DPP9 | |
| SCHEMBL14730183 | 0.83 | DPP4 (0.33) | DPP4DPP8DPP9DPP7KCNH2 | |
| SCHEMBL12064566 | 0.82 | MCHR1 (0.35) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730360 | 0.82 | MCHR1 (0.36) | MCHR1DPP4CCR5DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |