Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 18/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730243 | 0.85 | GPR119 (0.36) | — | |
| SCHEMBL14730362 | 0.81 | DPP4 (0.36) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730211 | 0.79 | NTRK1 (0.36) | — | |
| SCHEMBL14730244 | 0.77 | MCHR1 (0.35) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730365 | 0.76 | MCHR1 (0.34) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730360 | 0.76 | MCHR1 (0.36) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730284 | 0.75 | MCHR1 (0.36) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730359 | 0.75 | MCHR1 (0.36) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730188 | 0.74 | DPP4 (0.50) | MCHR1DPP4DPP8DPP9KCNH2 | |
| SCHEMBL14730234 | 0.74 | DPP4 (0.45) | DPP4DPP8DPP9KCNH2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |