Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.57 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197788 | 1.00 | RECQL (0.59) | RECQLGAACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13211802 | 0.92 | RECQL (0.72) | RECQLGAACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13073616 | 0.91 | ACHE (0.67) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL15017254 | 0.84 | VNN1 (0.65) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL15017250 | 0.84 | VNN1 (0.65) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL30589315 | 0.84 | VNN1 (0.65) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL30201416 | 0.83 | CHRNB2 (0.54) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14197786 | 0.83 | RECQL (0.82) | RECQLGAACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30480166 | 0.83 | CHRNB2 (0.57) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14275546 | 0.83 | CHRNB2 (0.57) | GAACHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026163-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |