Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248397 | 0.82 | LMNA (0.50) | MAPKAPK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14730815 | 0.80 | MEN1 (0.44) | MAPKAPK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14731470 | 0.73 | MAPKAPK2 (0.44) | MAPKAPK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14731471 | 0.70 | MAPKAPK2 (0.33) | MAPKAPK2 | |
| SCHEMBL14731462 | 0.69 | LMNA (0.55) | MAPKAPK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL3005560 | 0.66 | KDM4E (0.46) | MAPKAPK2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL16248398 | 0.64 | KIF11 (0.44) | MAPKAPK2KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL14731469 | 0.64 | MAPKAPK2 (0.31) | MAPKAPK2 | |
| SCHEMBL14730689 | 0.64 | KDM4E (0.47) | MAPKAPK2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14730760 | 0.64 | KDM4E (0.50) | MAPKAPK2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026163-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026162-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |