Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 9/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994243 | 0.78 | NOS3 (0.49) | ACHESRD5A1PDE3BPDE3A | |
| SCHEMBL8994244 | 0.77 | PDE3B (0.42) | PDE3BPDE3A | |
| SCHEMBL13730198 | 0.67 | ACHE (0.43) | ACHESRD5A1F7PARP1F3 | |
| SCHEMBL30029531 | 0.64 | ACHE (0.38) | ACHECTSD | |
| SCHEMBL22748074 | 0.64 | HTR2A (0.36) | ACHECTSD | |
| SCHEMBL29485963 | 0.63 | HRH4 (0.42) | ACHE | |
| SCHEMBL1090905 | 0.61 | HTR2A (0.41) | ACHEAHRCMA1F7PARP1 | |
| SCHEMBL18755275 | 0.61 | MAPT (0.38) | ACHESRD5A1TYMSCTSD | |
| SCHEMBL11036926 | 0.60 | NOS3 (0.41) | ACHECTSD | |
| SCHEMBL7463606 | 0.60 | MAPK1 (0.40) | ACHEAHRCMA1SRD5A1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027932-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING PREMATURE EJACULATION COMPRISING 8-HYDROXYCLOMIPRAMINE OR ITS SALT | KUHNIL PHARM. CO., LTD. (KR) | 2013-02-28 | — | — | WO | disclosed |