Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23519908 | 0.79 | NPC1 (0.47) | ALDH1A1LMNAMAPTTP53HSD17B10 | |
| SCHEMBL12432761 | 0.77 | TP53 (0.36) | ALDH1A1LMNAMAPTTP53HSD17B10 | |
| SCHEMBL21823142 | 0.75 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTTP53HSD17B10 | |
| SCHEMBL2232351 | 0.73 | PDE4B (0.33) | ALDH1A1LMNAMAPTTP53HSD17B10 | |
| SCHEMBL2231857 | 0.73 | GPR35 (0.36) | ALDH1A1LMNAMAPTTP53HSD17B10 | |
| SCHEMBL2232669 | 0.73 | — | — | |
| SCHEMBL2235201 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTNOTUM | |
| SCHEMBL21822980 | 0.72 | GPR35 (0.37) | ALDH1A1LMNAMAPTNOTUM | |
| SCHEMBL21823173 | 0.71 | PDPK1 (0.48) | LMNATP53HSD17B10 | |
| SCHEMBL21823128 | 0.71 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053370-A1 | THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROTEIN KINASES | HANMI SCIENCE CO., LTD. (KR) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053370-A1 | THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROTEIN KINASES | CDK2, TK1, DTYMK | ALDH1A1 2542/4885LMNA 4180/4885MAPT 1324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.