SCHEMBL1473153

SCHEMBL1473153

CC(C)(C)[Si](C)(C)OCCCCCCn1c2ccccc2c2cc(C=O)ccc21

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 5/20 0.60
PSEN1 P49768 4/20 0.41
PSEN2 P49810 4/20 0.41
APH1B Q8WW43 4/20 0.41
NCSTN Q92542 4/20 0.41
APH1A Q96BI3 4/20 0.41
PSENEN Q9NZ42 4/20 0.41
KDM4E B2RXH2 1/20 0.40
POLB P06746 1/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
CNR2 P34972 3/20 0.39
SRC P12931 2/20 0.38
MAOA P21397 4/20 0.38
MAOB P27338 4/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5660529 0.82 PTGER4 (0.70) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL5119647 0.82 PTGER4 (0.70) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL1472722 0.82 PGR (0.47) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL12750803 0.79 PTGER4 (0.63) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL4821945 0.79 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL28412652 0.79 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL31174405 0.79 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL5153575 0.79 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL28369278 0.79 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL28446594 0.79 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915428-B2 Photorefractive dendron compound, photorefractive dendrimer compound, method of preparing the same, photorefractive device using the same, and method of manufacturing the device SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-29 US disclosed
US-7915428-B2 Photorefractive dendron compound, photorefractive dendrimer compound, method of preparing the same, photorefractive device using the same, and method of manufacturing the device SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-29 US disclosed
US-20090223627-A1 PHOTOREFRACTIVE DENDRON COMPOUND, PHOTOREFRACTIVE DENDRIMER COMPOUND, METHOD OF PREREPARING THE SAME, PHOTOREFRACTIVE DEVICE USING THE SAME, AND METHOD OF MANUFACTURING THE DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090223627-A1 PHOTOREFRACTIVE DENDRON COMPOUND, PHOTOREFRACTIVE DENDRIMER COMPOUND, METHOD OF PREREPARING THE SAME, PHOTOREFRACTIVE DEVICE USING THE SAME, AND METHOD OF MANUFACTURING THE DEVICE KISS1R, CROCC, DBN1 PTGER4 2450/4885PSEN1 1642/4885PSEN2 1666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.