Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31127370 | 0.85 | CCR1 (0.58) | CCR1CCR8TGFBR1LMNAGRM5 | |
| SCHEMBL2242901 | 0.85 | CCR1 (0.58) | CCR1CCR8TGFBR1LMNAGRM5 | |
| SCHEMBL14733154 | 0.84 | CCR1 (0.48) | CCR1CCR8TGFBR1GAACYP2A6 | |
| SCHEMBL9217242 | 0.82 | LMNA (0.58) | CCR1CCR8TGFBR1LMNAGRM5 | |
| SCHEMBL10539246 | 0.81 | PDE2A (0.40) | CCR1CCR8HSP90AA1HSP90AB1TGFBR1 | |
| SCHEMBL9565637 | 0.80 | RAB9A (0.56) | CCR1CCR8TGFBR1GAALMNA | |
| SCHEMBL10537342 | 0.78 | CCR1 (0.42) | CCR1CCR8HSP90AA1TGFBR1GAA | |
| SCHEMBL15131532 | 0.76 | CCR1 (0.60) | CCR1CCR8TGFBR1GRM5CYP2A6 | |
| SCHEMBL10541408 | 0.76 | NPC1 (0.42) | CCR1CCR8HSP90AA1TGFBR1GAA | |
| SCHEMBL14732985 | 0.76 | FFAR1 (0.40) | CCR1CCR8TGFBR1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |