Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD69 | Q07108 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | CXCR5 | P32302 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108268 | 0.87 | CD69 (0.44) | CD69ADRA2AADRA2BADRA2CCXCR5 | |
| SCHEMBL1724552 | 0.85 | CD69 (0.49) | CD69ADRA2AADRA2BADRA2CCXCR5 | |
| SCHEMBL8556505 | 0.84 | GSTA1 (0.41) | CD69ADRA2AADRA2BADRA2CCXCR5 | |
| SCHEMBL1398342 | 0.76 | HSD17B10 (0.37) | CD69ADRA2AADRA2BADRA2CCXCR5 | |
| SCHEMBL1473043 | 0.75 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CHPGDTSHR | |
| SCHEMBL1628363 | 0.74 | TSHR (0.50) | ADRA2AADRA2BADRA2CHPGDTSHR | |
| SCHEMBL10648647 | 0.72 | KMT2A (0.47) | ADRA2AADRA2BADRA2CCXCR5HPGD | |
| SCHEMBL5079771 | 0.72 | SCN4A (0.47) | ADRA2AADRA2BADRA2CCXCR5TSHR | |
| SCHEMBL1858805 | 0.72 | CA12 (0.39) | ADRA2AADRA2BADRA2CCXCR5HPGD | |
| SCHEMBL16213529 | 0.72 | MAPT (0.39) | ADRA2AADRA2BADRA2CHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915438-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7271259-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2007-09-18 | — | — | US | disclosed |