Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398342 | 0.79 | HSD17B10 (0.37) | ADRA2AADRA2BADRA2CALDH1A1SMN1; SMN2 | |
| SCHEMBL9253029 | 0.79 | ALDH1A1 (0.36) | ALDH1A1CYP3A4SMN1; SMN2PPARGPPARD | |
| SCHEMBL5082696 | 0.76 | FFAR4 (0.40) | TNKSTNKS2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL1473328 | 0.75 | CD69 (0.48) | ADRA2AADRA2BADRA2CCYP3A4HSD17B10 | |
| SCHEMBL1471513 | 0.72 | PTPRB (0.47) | TNKSTNKS2ALDH1A1CYP3A4PPARG | |
| SCHEMBL20226270 | 0.68 | GABRA1 (0.44) | CYP3A4HSD17B10MAPTALOX15MEN1 | |
| SCHEMBL2108268 | 0.68 | CD69 (0.44) | ADRA2AADRA2BADRA2CALDH1A1CYP3A4 | |
| SCHEMBL215399 | 0.67 | XDH (0.50) | TNKSTNKS2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL22701030 | 0.66 | ALDH1A1 (0.39) | ADRA2AADRA2BADRA2CALDH1A1CYP3A4 | |
| SCHEMBL7782792 | 0.64 | ALDH1A1 (0.61) | ADRA2AADRA2BADRA2CALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915438-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7271259-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2007-09-18 | — | — | US | disclosed |