Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.45 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.42 |
| ▸ | HTR3B | O95264 | 2/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733340 | 0.88 | DRD2 (0.43) | KMT2AMEN1NPC1RAB9AHRH4 | |
| SCHEMBL14733339 | 0.86 | HRH4 (0.45) | KMT2AMEN1NPC1RAB9AHRH4 | |
| SCHEMBL2328041 | 0.84 | HTR2A (0.44) | KMT2AMEN1NPC1RAB9AHRH4 | |
| SCHEMBL14733343 | 0.80 | KMT2A (0.44) | KMT2AHRH4HTR3AHTR3EHTR3B | |
| SCHEMBL2333603 | 0.77 | MEN1 (0.41) | KMT2AMEN1NPC1RAB9AHRH4 | |
| Hydrochloric Acid SCHEMBL2360446 | 0.76 | MEN1 (0.40) | KMT2AMEN1NPC1RAB9AHRH4 | |
| SCHEMBL14733342 | 0.75 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AHTR3A | |
| SCHEMBL2360469 | 0.74 | HRH4 (0.45) | KMT2AMEN1NPC1RAB9AHRH4 | |
| SCHEMBL2333076 | 0.73 | HRH4 (0.42) | KMT2AMEN1NPC1RAB9AHRH4 | |
| SCHEMBL2329791 | 0.69 | HRH4 (0.37) | KMT2AMEN1NPC1RAB9AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053372-A1 | 5-HT RECEPTOR MODULATORS | CAMBRIDGE ENTERPRISE LIMITED | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053372-A1 | 5-HT RECEPTOR MODULATORS | HTR1B, HTR5A, HTR1A | KMT2A 2405/4885MEN1 1036/4885NPC1 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.