SCHEMBL14733795

SCHEMBL14733795

c1cc(-c2ccc3c(c2)c2ccccc2n3-c2ccc3sc4ccccc4c3c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GPR3 P46089 1/20 0.37
PIM3 Q86V86 1/20 0.34
TSPO P30536 1/20 0.33
MAPT P10636 4/20 0.33
RAB9A P51151 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX5 P09917 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
RAC2 P15153 1/20 0.32
RAC3 P60763 1/20 0.32
CDC42 P60953 1/20 0.32
RAC1 P63000 1/20 0.32
CYP1A2 P05177 1/20 0.32
HSD17B10 Q99714 1/20 0.31
EDNRB P24530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687794 1.00 KDM4E (0.40) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL14649090 1.00 KDM4E (0.40) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL14867992 0.99 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687800 0.99 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL19258233 0.99 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687756 0.99 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687697 0.99 ATM (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687718 0.99 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL16641508 0.97 ATM (0.41) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL21481273 0.97 ATM (0.41) KDM4EATML3MBTL1GPR3PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216427-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-07-07 US disclosed
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20140339529-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2014-11-20 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 KDM4E 3396/4885ATM 2966/4885L3MBTL1 2272/4885
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 KDM4E 1228/4885ATM 3768/4885L3MBTL1 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.