SCHEMBL19258233

SCHEMBL19258233

c1cc(-c2cccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6sc7ccc(-n8c9ccccc9c9ccccc98)cc7c6c5)ccc43)c2)cc(-c2ccc3sc4ccccc4c3c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GPR3 P46089 1/20 0.36
PIM3 Q86V86 1/20 0.34
TSPO P30536 1/20 0.32
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALOX5 P09917 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31
CYP1A2 P05177 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1687718 1.00 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687800 1.00 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687756 1.00 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL14867992 1.00 KDM4E (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL14649090 0.99 KDM4E (0.40) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687794 0.99 KDM4E (0.40) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL14733795 0.99 KDM4E (0.40) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL1687697 0.97 ATM (0.39) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL20706683 0.97 GPR3 (0.38) KDM4EATML3MBTL1GPR3PIM3
SCHEMBL14649455 0.97 KDM4E (0.41) KDM4EATML3MBTL1GPR3PIM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4401530-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-07-17 EP disclosed
EP-3816175-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-07-17 EP disclosed
EP-3858945-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-11-29 EP disclosed
EP-4282863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-11-29 EP disclosed
EP-4265626-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-10-25 EP disclosed
EP-3301088-B1 CONDENSED PYRIDINES AS ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2023-08-30 EP disclosed
EP-4185086-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-05-24 EP disclosed
EP-4141010-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-03-01 EP disclosed
EP-4016659-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2022-06-22 EP disclosed
US-20220177492-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-06-09 US disclosed
EP-3789379-A1 4-PHENYLBENZO[G]QUINAZOLINE OR 4-(3,5-DIMETHYLPHENYLBENZO[G]QUINAZOLINE IRIDIUM COMPLEXES FOR USE AS NEAR-INFRARED OR INFRARED EMITTING MATERIALS IN OLEDS Universal Display Corporation (US) 2021-03-10 EP disclosed
EP-3783006-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-02-24 EP disclosed
EP-3321258-B1 4-PHENYLBENZO[G]QUINAZOLINE OR 4-(3,5-DIMETHYLPHENYLBENZO[G]QUINAZOLINE IRIDIUM COMPLEXES FOR USE AS NEAR-INFRARED OR INFRARED EMITTING MATERIALS IN OLEDS UNIVERSAL DISPLAY CORP (US) 2020-12-23 EP disclosed
EP-3444258-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-07-01 EP disclosed
US-20190214582-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-07-11 US disclosed
EP-3492480-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 EP disclosed
EP-3444258-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-02-20 EP disclosed
EP-3354654-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-08-01 EP disclosed
EP-3321258-A1 4-PHENYLBENZO[G]QUINAZOLINE OR 4-(3,5-DIMETHYLPHENYLBENZO[G]QUINAZOLINE IRIDIUM COMPLEXES FOR USE AS NEAR-INFRARED OR INFRARED EMITTING MATERIALS IN OLEDS Universal Display Corporation (US) 2018-05-16 EP disclosed
EP-3205658-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177492-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OPRD1 KDM4E 2503/4885ATM 3482/4885L3MBTL1 1618/4885
US-20190214582-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP KDM4E 4165/4885ATM 3357/4885L3MBTL1 974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.