Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026453 | 0.80 | CYP4F2 (0.49) | CYP4F2CYP4A11LIPG | |
| SCHEMBL7542307 | 0.79 | CYP2A6 (0.54) | TLR8KDM4EALDH1A1MAPTCYP1A2 | |
| SCHEMBL3827720 | 0.79 | LIPG (0.48) | CYP4F2CYP4A11LIPG | |
| SCHEMBL24336330 | 0.78 | ATM (0.50) | TLR8KDM4EALDH1A1MAPTCYP1A2 | |
| SCHEMBL28046693 | 0.78 | TLR8 (0.61) | TLR8MAPTLIPG | |
| SCHEMBL14733918 | 0.77 | SLC2A1 (0.57) | KDM4EALDH1A1SLC2A1 | |
| SCHEMBL14733919 | 0.77 | BCHE (0.42) | TLR8KDM4EMAPTLIPGBCHE | |
| SCHEMBL11227235 | 0.76 | TLR8 (0.59) | TLR8MAPTLIPG | |
| SCHEMBL11229645 | 0.76 | TLR8 (0.59) | TLR8MAPTLIPG | |
| SCHEMBL14733857 | 0.76 | SLC2A1 (0.56) | KDM4EALDH1A1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331552-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-02-27 | — | — | EP | disclosed |