Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.43 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781575 | 1.00 | TNF (0.54) | TNFTSHRLMNAMDM4TP53 | |
| SCHEMBL16131612 | 1.00 | TNF (0.54) | TNFTSHRLMNAMDM4TP53 | |
| SCHEMBL8618364 | 1.00 | TNF (0.54) | TNFTSHRLMNAMDM4TP53 | |
| SCHEMBL31501986 | 0.93 | TNF (0.49) | TNFTSHRLMNAMDM4TP53 | |
| SCHEMBL14733502 | 0.91 | TNF (0.53) | TNFTSHRLMNAMDM4TP53 | |
| SCHEMBL1737629 | 0.91 | LMNA (0.55) | TNFTSHRLMNAMDM4TP53 | |
| SCHEMBL31501999 | 0.91 | TNF (0.53) | TNFTSHRLMNAKMT2ACYP2D6 | |
| SCHEMBL8558498 | 0.90 | TNF (0.49) | TNFMDM4TP53CASP3SLC17A5 | |
| SCHEMBL8558500 | 0.90 | TNF (0.49) | TNFMDM4TP53CASP3SLC17A5 | |
| SCHEMBL4983320 | 0.89 | TNF (0.44) | TNFTSHRLMNAKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053543-A1 | PEPTIDE CLEARING AGENTS | MOLOGIC LTD (GB) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053543-A1 | PEPTIDE CLEARING AGENTS | ANPEP, DNPEP, ENPEP | TNF 4058/4885TSHR 2669/4885LMNA 3564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.