Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133106 | 0.88 | KMT2A (0.40) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL5950355 | 0.85 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL25376789 | 0.84 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL30634592 | 0.83 | KMT2A (0.55) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL26841555 | 0.82 | GAA (0.40) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL4085561 | 0.81 | LMNA (0.41) | MEN1KMT2AALDH1A1RAB9APOLB | |
| SCHEMBL22325943 | 0.80 | LMNA (0.40) | MEN1KMT2AALDH1A1RAB9APOLB | |
| SCHEMBL29126560 | 0.79 | KMT2A (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL30893472 | 0.79 | KMT2A (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL31607327 | 0.79 | KMT2A (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027794-A1 | NOVEL COMPOUND AND USE THEREOF AS PDE10 INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2013-02-28 | — | — | WO | disclosed |