Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24202566 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL27385695 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL24202568 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL1653800 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRGPR35GLAKMT2A | |
| Hydrochloric Acid SCHEMBL10522516 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL10974753 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRGPR35GLAKMT2A | |
| SCHEMBL14734358 | 0.85 | MEN1 (0.52) | ALDH1A1TSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25376789 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL15532063 | 0.81 | TSHR (0.53) | ALDH1A1TSHRGPR35KMT2AMEN1 | |
| SCHEMBL1653885 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRGPR35GLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060106262-A1 | Electrooptic chromophores with large optical birefringence for applications at high speed and short wavelengths | OPTIMER PHOTONICS, INC. | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106262-A1 | Electrooptic chromophores with large optical birefringence for applications at high speed and short wavelengths | EYA2, CRY2, EYA3 | ALDH1A1 1560/4885TSHR 4278/4885GPR35 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.