Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SCN4A | P35499 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199718 | 0.75 | ALDH1A1 (0.43) | ALDH1A1RECQLGAACYP3A4CYP2D6 | |
| SCHEMBL1412775 | 0.75 | ALDH1A1 (0.50) | ALDH1A1RECQLGAATAAR1CYP3A4 | |
| SCHEMBL9440336 | 0.72 | ALDH1A1 (0.50) | ALDH1A1RECQLGAACYP3A4CYP2D6 | |
| SCHEMBL8107481 | 0.70 | ALDH1A1 (0.41) | ALDH1A1RECQLSCN4ATAAR1SCN9A | |
| SCHEMBL10385266 | 0.69 | ALDH1A1 (0.47) | ALDH1A1RECQLGAAMTNR1AMTNR1B | |
| SCHEMBL8827205 | 0.68 | ALDH1A1 (0.46) | ALDH1A1RECQLGAACYP3A4CYP2D6 | |
| SCHEMBL5177631 | 0.67 | ALDH1A1 (0.43) | ALDH1A1RECQLSCN4ACYP3A4CYP2D6 | |
| SCHEMBL5674229 | 0.67 | ALDH1A1 (0.43) | ALDH1A1RECQLSCN4ASLC6A4LTA4H | |
| SCHEMBL28817490 | 0.67 | LTA4H (0.41) | SCN4ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3974341 | 0.67 | ALDH1A1 (0.44) | ALDH1A1RECQLGAACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541580-B1 | Sulfotransferase inhibitors | SEIKAGAKU KOGYO CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |