Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506617 | 0.83 | LMNA (0.42) | ALDH1A1ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL4556683 | 0.78 | SCN1A (0.57) | ADRA2ALMNAKDM4ESLC6A2SLC6A4 | |
| SCHEMBL7120235 | 0.78 | ALDH1A1 (0.46) | ALDH1A1RECQLADRA2ALMNAKDM4E | |
| SCHEMBL28747058 | 0.77 | ALDH1A1 (0.45) | ALDH1A1RECQLADRA2AADRA2CLMNA | |
| SCHEMBL5549297 | 0.76 | CHRNB2 (0.51) | ALDH1A1RECQLSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10652751 | 0.76 | TAAR1 (0.41) | ALDH1A1ADRA2AADRA2CLMNAHIF1A | |
| SCHEMBL5501342 | 0.76 | LTA4H (0.44) | DPP4F2 | |
| SCHEMBL5550370 | 0.75 | GSR (0.50) | ALDH1A1RECQLADRA2ALMNAKDM4E | |
| SCHEMBL29633537 | 0.75 | TRPA1 (0.44) | ALDH1A1RECQLADRA2AADRA2CLMNA | |
| SCHEMBL4025487 | 0.75 | ALDH1A1 (0.43) | ALDH1A1RECQLADRA2ALMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105482094-A | Non-ionic water-borne epoxy resin and preparation method thereof | JIANGSU COLOURFUL NEW BUILDING MAT IND CO LTD | 2016-04-13 | — | — | CN | disclosed |
| EP-1791835-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| EP-1786792-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | Astellas Pharma Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006028269-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 IHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006011631-A2 | THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY | ASTELLAS PHARMA INC. (JP) | 2006-02-02 | — | — | WO | disclosed |