Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734645 | 0.91 | HTT (0.51) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL14734665 | 0.87 | RAB9A (0.44) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL14722525 | 0.86 | POLB (0.50) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL14722523 | 0.86 | POLB (0.50) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL14734663 | 0.83 | HTT (0.58) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734667 | 0.83 | MAOB (0.43) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL14734650 | 0.81 | MAPT (0.43) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL15862274 | 0.81 | TDP1 (0.50) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL15862275 | 0.81 | TDP1 (0.50) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL14734680 | 0.79 | MAPT (0.43) | HTTPOLBAPEX1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |