Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28990006 | 0.75 | MAOA (0.32) | — | |
| Hydrochloric Acid SCHEMBL4634094 | 0.74 | GPR3 (0.35) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL911069 | 0.74 | GPR3 (0.35) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL6908726 | 0.74 | GPR3 (0.35) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL28436054 | 0.74 | GPR3 (0.32) | GPR3 | |
| SCHEMBL29385315 | 0.73 | GPR3 (0.38) | GPR3HTR2APOLBPBRM1TNKS2 | |
| SCHEMBL5356718 | 0.73 | GPR3 (0.38) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL27561373 | 0.72 | GPR3 (0.34) | GPR3HTR2ATNKS2 | |
| Hydrochloric Acid SCHEMBL3627628 | 0.72 | GPR3 (0.34) | GPR3HTR2A | |
| SCHEMBL9146467 | 0.71 | GPR3 (0.37) | GPR3HTR2APOLBPBRM1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279485-B | Polyvinyls, catalyst for olefines polymerizing ingredient, the catalyst for olefines polymerizing comprising the ingredient and the method using catalyst production polyvinyls | 日本聚乙烯株式会社 | 2018-10-02 | — | — | CN | disclosed |
| CN-106279485-A | Polyvinyls, polythylene resin composition and application thereof, catalyst for olefines polymerizing composition, the catalyst for olefines polymerizing comprising described composition and the method using described Catalyst Production polyvinyls | 日本聚乙烯株式会社 | 2017-01-04 | — | — | CN | disclosed |
| CN-103582669-B | Ethylene polymer, polyethylene resin composition and use thereof, catalyst component for olefin polymerization, catalyst for olefin polymerization comprising the component, and method for producing ethylene polymer using the catalyst | 日本聚乙烯株式会社 | 2016-08-31 | — | — | CN | disclosed |
| EP-1880986-B1 | PROCESS FOR PRODUCING SATURATED ALIPHATIC HYDROCARBONS, AND LUBRICANT COMPOSITIONS THEREOF | IDEMITSU KOSAN CO (JP) | 2013-03-06 | — | — | EP | disclosed |