Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378285 | 0.91 | LMNA (0.38) | LMNASSTR4P2RY1HTTMAPT | |
| SCHEMBL8374350 | 0.86 | SMN1; SMN2 (0.39) | LMNASSTR4HTTMAPTSMN1; SMN2 | |
| SCHEMBL8375973 | 0.84 | SSTR4 (0.42) | LMNASSTR4MEN1MAPTKMT2A | |
| SCHEMBL14735535 | 0.84 | MAPT (0.41) | LMNAP2RY1HTTMAPTKMT2A | |
| SCHEMBL8374349 | 0.83 | FAAH (0.40) | LMNASSTR4P2RY1HTTMEN1 | |
| SCHEMBL8883717 | 0.82 | CTSA (0.44) | TSHRLMNATAS1R3TAS1R1HTT | |
| Hydrochloric Acid SCHEMBL8374272 | 0.81 | LMNA (0.42) | TSHRLMNASSTR4MAPTHPGD | |
| SCHEMBL8375877 | 0.81 | FAAH (0.46) | LMNAP2RY1HTTMEN1MAPT | |
| SCHEMBL8374372 | 0.80 | FAAH (0.43) | LMNAP2RY1HTTMEN1MAPT | |
| SCHEMBL8374641 | 0.80 | GAA (0.46) | LMNASSTR4MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900202-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041103-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |
| EP-0650960-B1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0650960-A1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |