Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516994 | 0.79 | HSD17B10 (0.48) | HSD17B10TRPA1LMNACYP2A6AHR | |
| SCHEMBL3668723 | 0.77 | AHR (0.52) | HSD17B10LMNACYP2A6AHRMAOB | |
| SCHEMBL3851036 | 0.77 | AHR (0.52) | HSD17B10LMNACYP2A6AHRMAOB | |
| SCHEMBL11438751 | 0.74 | AHR (0.54) | HSD17B10LMNACYP2A6AHRMAOB | |
| SCHEMBL7519973 | 0.74 | MAOB (0.46) | TRPA1LMNACYP2A6MAOBALOX5 | |
| SCHEMBL3654206 | 0.74 | MAOB (0.46) | TRPA1LMNACYP2A6MAOBALOX5 | |
| SCHEMBL432740 | 0.74 | AHR (0.54) | HSD17B10LMNACYP2A6AHRMAOB | |
| SCHEMBL1425165 | 0.74 | AHR (0.54) | HSD17B10LMNACYP2A6AHRMAOB | |
| SCHEMBL2657529 | 0.74 | MAOB (0.46) | TRPA1LMNACYP2A6MAOBALOX5 | |
| SCHEMBL6158447 | 0.73 | CHRM5 (0.50) | MAOBCYP1A2ALOX5FBP1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763302-B1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-06 | — | — | EP | disclosed |