Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.48 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038387 | 0.86 | GAA (0.67) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL6151129 | 0.86 | GAA (0.67) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL822302 | 0.86 | KMT2A (0.59) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL29468572 | 0.86 | KMT2A (0.59) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL3884518 | 0.84 | HTR6 (0.61) | HTTL3MBTL1TDP1GAAABCC9 | |
| Hydrochloric Acid SCHEMBL11279258 | 0.84 | KMT2A (0.57) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL15607666 | 0.84 | KMT2A (0.57) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL9788125 | 0.81 | RAPGEF4 (0.56) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL20198361 | 0.81 | ALDH1A1 (0.54) | HTTL3MBTL1TDP1GAAABCC9 | |
| SCHEMBL18454126 | 0.81 | HTT (0.50) | HTTL3MBTL1TDP1GAAABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565185-A1 | [5,6]HETEROCYCLIC COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-03-06 | — | — | EP | disclosed |