Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ARNT | P27540 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481398 | 0.87 | PTGS2 (0.36) | CHRM2CHRM1CHRM3ARNTEPAS1 | |
| SCHEMBL2510401 | 0.87 | PGR (0.40) | CHRM2CHRM1CHRM3ARNTEPAS1 | |
| SCHEMBL421510 | 0.84 | MAPK14 (0.45) | XDHSLC22A12RPA1SLC9A1 | |
| SCHEMBL2506075 | 0.82 | CNR2 (0.39) | XDHARNTEPAS1ACLYPTGDR2 | |
| SCHEMBL420399 | 0.79 | MAPK14 (0.51) | CHRM2CHRM1CHRM3PGRPTGS2 | |
| SCHEMBL2482567 | 0.73 | MAPK14 (0.38) | CHRM2CHRM1CHRM3ARNTEPAS1 | |
| SCHEMBL422505 | 0.72 | MAPK14 (0.41) | CHRM2CHRM1CHRM3PGR | |
| SCHEMBL2505963 | 0.71 | FNTA (0.41) | CHRM3ARNTEPAS1PGRPTGDR2 | |
| SCHEMBL422068 | 0.70 | MAPK14 (0.50) | PTGS2RPA1SLC9A1 | |
| SCHEMBL2509882 | 0.70 | S1PR1 (0.36) | CHRM3ARNTEPAS1PGRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376482-B1 | SUBSTITUTED (THIOPHENYL-CARBONYL)IMIDAZOLIDINONES, AND USE THEREOF | AICURIS GMBH & CO KG (DE) | 2013-03-06 | — | — | EP | disclosed |