Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14735978 | 0.90 | HSD17B3 (0.37) | HSD17B3CYP2A6 | |
| SCHEMBL7799447 | 0.69 | — | — | |
| SCHEMBL14735918 | 0.65 | MAPT (0.36) | LMNATSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL14752281 | 0.64 | TP53 (0.33) | TP53LMNACYP3A4HSD17B3TSHR | |
| SCHEMBL22171540 | 0.64 | TP53 (0.33) | TP53LMNACYP3A4HSD17B3TSHR | |
| SCHEMBL14752296 | 0.61 | TP53 (0.31) | TP53CYP3A4HSD17B3 | |
| SCHEMBL22171523 | 0.60 | GRIA1 (0.33) | TP53LMNAHTTCYP3A4TSHR | |
| SCHEMBL22174669 | 0.59 | TP53 (0.33) | TP53LMNACYP3A4TSHRALDH1A1 | |
| SCHEMBL7646750 | 0.59 | S100A4 (0.48) | — | |
| SCHEMBL7793703 | 0.57 | TP53 (0.36) | TP53LMNACYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059996-A1 | Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings | THE JOHNS HOPKINS UNIVERSITY | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059996-A1 | Boron-Containing PI-Electron Materials Incorporating Formally Aromatic and Neutral Borepin Rings | PNN, CIAPIN1, VNN1 | TP53 3605/4885LMNA 245/4885HTT 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.